Sam Rockwell Wolf (voice) Marc Maron Snake (voice) Craig Robinson Shark (voice) Anthony Ramos Piranha (voice) Awkwafina Tarantula (voice) Danielle Brooks Kitty Kat (voice) Maria Bakalova Pigtail Petrova (voice) Natasha Lyonne Doom aka Susan (voice) Zazie Beetz Diane Foxington (voice) Richard Ayoade Professor Marmalade (voice) Alex Borstein Commissioner Misty Luggins (voice) Lilly Singh Tiffany Fluffit (voice) Omid Djalili Mr. Soliman (voice) Colin Jost Mr. Moon (voice) Jaime Camil Handsome Jorge Garcia (voice) Jorge R. Gutierrez Lucha Spectator (voice) Joey Naber Servant / Cairo Cop 1 (voice) Monia Ayachi Cairo Security Guard 1 (voice) Jaylen Moore Cairo Security Guard 2 (voice) Arthur Ortiz Motorist / Macho Disco / Officiant / Prison Guard (voice) Michael Godere Bank Manager (voice) Jason Griffith Interviewer 1 / Warden / Jim (voice) Shelby Young Interviewer 2 / Bride (voice) Bridget Hoffman Interviewer 3 / Aunt Sharon (voice) Joel Steingold Interviewer 4 (voice) Christopher Knights Narrator (voice) Kelly Stables Maureen / Jenny (voice) Ashley Lambert Deputy / Computer Voice (voice) Juan Pacheco Angry Lucha Fan 1 & 2 (voice) David Michie Angry Lucha Fan 3 (voice)