Bobby Cannavale Max Bernal William A. Fitzgerald Ezra Bernal Robert De Niro Stan Bernal Rose Byrne Jenna Vera Farmiga Grace Whoopi Goldberg Jayne Rainn Wilson Nick Tony Goldwyn Bruce Jackson Frazer Ridgeway Greer Barnes Greer Tess Goldwyn Ms. Cathro Ella Ayberk Dr. Irina Tamarova Lois Robbins Susan Alex Plank Dr. Kaplan Daphne Rubin-Vega Agent Margo Jenkins Matilda Lawler Ruby Joe Pacheco Special Agent Costa Amy Sheehan Mrs. C. Geoffrey Owens Robert Segal Barzin Akhavan Dr. Jeffrey Wells Donna Vivino Noreen, Woman in Bar Jacqueline Nwabueze Sister Margaret John Donovan Wilson Sheriff Tom Joshua Hinck Tim David Marciano Detective Harrelson Dov Davidoff Self Brian Donahue Bouncer Myra Lucretia Taylor Margo Jennifer Plotzke Security Guard Jack Parrish Classmate Alex Barber Ezra's Classmate Julia Linger Waitress Skyler Wenger Classroom Kid Jimmy Kimmel Jimmy Kimmel Guillermo Rodriguez Guillermo Rodriguez Zoe Cali Cally Emma Willmann Self Mia Caro Agent Pena Bev Sheehan Waitress at Diner