Amy Poehler Joy (voice) Maya Hawke Anxiety (voice) Kensington Tallman Riley (voice) Liza Lapira Disgust (voice) Phyllis Smith Sadness (voice) Lewis Black Anger (voice) Tony Hale Fear (voice) Ayo Edebiri Envy (voice) Adèle Exarchopoulos Ennui (voice) Lilimar Valentina (voice) Grace Lu Grace (voice) Sumayyah Nuriddin-Green Bree (voice) Diane Lane Mom (voice) Kyle MacLachlan Dad (voice) Paul Walter Hauser Embarrassment (voice) Yvette Nicole Brown Coach Roberts (voice) Ron Funches Bloofy (voice) James Austin Johnson Pouchy (voice) Yong Yea Lance Slashblade (voice) Steve Purcell Deep Dark Secret (voice) Dave Goelz Mind Cop Frank (voice) Kirk R. Thatcher Foreman (voice) Frank Oz Mind Cop Dave (voice) June Squibb Nostalgia (voice) Paula Pell Mom's Anger (voice) Paula Poundstone Forgetter Paula (voice) John Ratzenberger Fritz (voice) Sarayu Blue Margie (voice) Flea Jake (voice) Bobby Moynihan Forgetter Bobby (voice)