Bruce Willis RJ (voice) Garry Shandling Verne (voice) Steve Carell Hammy (voice) Wanda Sykes Stella (voice) William Shatner Ozzie (voice) Nick Nolte Vincent (voice) Thomas Haden Church Dwayne (voice) Allison Janney Gladys (voice) Eugene Levy Lou (voice) Catherine O'Hara Penny (voice) Avril Lavigne Heather (voice) Omid Djalili Tiger (voice) Shane Baumel Spike (voice) Madison Davenport Quillo (voice) Ariel Winter (voice) Michaela Jill Murphy (voice) Paul Butcher Skeeter (voice) Jessica DiCicco Shelby (voice) Debra Wilson Debbie (voice) Jeannie Elias Janis (voice) Geoffrey Pomeroy Ranger (voice) Joel McCrary Dr. Dennis (voice) Brian Stepanek Nugent the Dog (voice) Kirk Baily (voice) Michelle Ruff (voice) Nicholas Guest (voice) Bridget Hoffman (voice) Marcelo Tubert (voice)